
Change is an inevitable part of life. However, many of the changes that negatively affect how we look and feel stem from specific biological shifts that can be traced, understood, and addressed—rather than simply accepted.
Over time, our bodies produce fewer peptides, affecting everything from our skin and hair to our metabolism and energy levels. Peptides may be small, but at Pearlman Aesthetic Surgery, we’re using them to make a big impact on people’s everyday lives.
Here’s how we’re redefining wellness with peptide injections in Manhattan.
What are peptides?
Found in every cell within the human body, peptides are chains of amino acids, which are the building blocks of proteins. Peptides carry messages throughout the body to initiate and regulate essential processes, such as skin repair and metabolic balance.
What is peptide therapy?
Peptide therapy counteracts the natural decline in peptides that can occur with age, chronic stress, and certain medical conditions, such as diabetes, to improve biological function. Different peptides have different structures, and their unique sequence of amino acids determines their function—whether that’s regenerating tissue or balancing your hormones.
This makes peptides a versatile tool for achieving your beauty and wellness goals. However, to achieve safe and meaningful results from peptide therapy, your provider must not only understand the science behind peptides, but also understand your unique biology.
What to Expect From Peptide Therapy
We offer peptide therapy in the form of peptide injections in Manhattan, delivering concern-specific peptides directly into your bloodstream. Unlike topical creams or oral formulations, this delivery method allows peptides to bypass your skin and digestive system, where they break down. Through injections, peptides remain potent and absorb more efficiently, providing more noticeable results in less time.
You may choose to visit our office for your injections or to administer them yourself at home. If you choose to perform injections yourself, we’ll walk you through the process to ensure you feel confident.
Most patients’ peptide therapy plans last between 4 and 6 weeks, but the length of your program and the frequency of injections depend on your goals and the chosen peptides. Because peptides act at the cellular level, they require minimal downtime and often provide noticeable improvements within 2 to 4 weeks. To maintain your results, your provider will craft a long-term plan, which may consist of healthy lifestyle changes and ongoing, but less frequent, peptide therapy.
Our Personalized Approach to Peptide Therapy
At Pearlman Aesthetic Surgery, peptide therapy is a deeply personalized experience designed to work in harmony with your body’s natural processes. Our approach isn’t standardized.

Your journey always begins with a comprehensive consultation, where we complete detailed lab work and openly discuss your struggles, aspirations, medical history, and lifestyle. Only then can we determine the appropriate peptide or combination of peptides for your situation.
Going beyond asking you how you feel after receiving peptide injections in Manhattan, we also offer epigenetic testing to measure your progress. These tests evaluate changes in your genes and your “biological age,” giving us—and you—a more in-depth understanding of your overall health.
Anti-Aging & Beauty Peptides
We understand that when you don’t identify with your reflection, looking older than you feel, you can face a personal disconnect with your appearance. That disconnect can impact how you show up at work, for your family, and for yourself, so investing in yourself isn’t selfish.
Some of our most common anti-aging peptides include:
- Copper (GHK-Cu): Stimulates collagen and elastin production to reduce the appearance of fine lines and aging skin.
- Ipamorelin (CJC-1295): Supports natural growth hormone production to encourage cellular repair, improving skin elasticity.
- Pentadecapeptide (BPC-157): Calms inflammation and accelerates the natural healing process to strengthen skin.
Specifically designed to slow the signs of visible aging, our beauty-focused peptide injections in Manhattan boost collagen and elastin production. While collagen proteins create your skin’s internal structure, elastin fibers give it its flexibility. Both decline with age, making your skin more prone to gravity and damage—leading to wrinkles, sun spots, and sagging skin. Through peptide therapy, we rebuild your skin from the inside out for natural yet noticeable improvements in your skin’s texture, tone, and overall radiance.
Additional Treatments for Graceful Aging
At Pearlman Aesthetic Surgery, we empower beauty®, and that looks different for everyone. For those looking to enhance the regenerative results from peptide therapy without surgery, we may recommend EZGel PRF in NYC. Derived from a sample of your own blood, PRF (platelet-rich fibrin) contains natural growth factors that, when injected, stimulate collagen production to restore lost volume and elasticity—offering a natural, longer-lasting alternative to dermal fillers.
That being said, traditional fillers still have their place. Unlike PRF, dermal fillers provide immediate volume. They also offer more controllable results, making them more ideal for precise enhancements like the lips, and PRF more suitable for broader areas, such as tear troughs.

While our anti-aging peptides gradually smooth surface-level lines by boosting collagen, wrinkle relaxers like Botox work by limiting specific muscle movements. Typically, patients looking to address static wrinkles and improve their overall skin quality benefit from peptides. Those seeking more immediate, dramatic relief from dynamic wrinkles, which form from repeated expressions like smiling, may turn to Botox.
Both injectable approaches offer safe and effective results, but work differently. Combining Botox with peptides offers a holistic anti-aging strategy, with peptides rebuilding your skin’s internal structure to support its long-term health, and Botox targeting expression lines. Together, they can create a more youthful, harmonious appearance without overcorrection and prevent future wrinkles from forming—both on the surface and deeper within your skin.
Performance & Recovery Peptides
Declining stamina and slower recovery can limit your body’s potential. As you age or continue to push your body, it struggles to produce energy or heal itself like it once did, prolonging the inflammatory phase.
By restoring your body’s resilience, our targeted peptide injections in Manhattan help you train harder, recover faster, and maintain peak performance. At Pearlman Aesthetic Surgery, we offer a range of peptides to support optimal performance at every stage, including:
- Accelerating the healing of tendons, muscles, and ligaments.
- Boosting your metabolism for enhanced energy and recovery.
- Encouraging lean muscle development and endurance.
- Enhancing tissue repair after intense physical activity or injury.
These peptides aren’t just for athletes. They help people of all ages and activity levels regain their strength, helping them recover from surgery, injury, and life’s everyday demands.
Additional Treatments for Boosting Performance
Peptides are powerful on their own, but pairing them with targeted wellness infusions (IVs) can maximize their impact. Doctors have relied on IVs for decades, using them to hydrate patients more efficiently than they can by drinking water. Water makes up more than 50% of the human body, so hydration plays an essential role in energy production and recovery—both mental and physical.
Our intentionally formulated infusions also deliver vital nutrients to your bloodstream, working more effectively than oral vitamin supplements. These infusions ensure your cells have the materials they need to complete important processes like energy production and muscle repair, while peptides signal when to start the process.

We may also recommend peptide injections in Manhattan for patients recovering from aesthetic surgeries, such as a facelift, or non-surgical skin tightening treatments. Peptides help your body control inflammation and repair tissue, promoting a more comfortable, shorter recovery experience and supporting your skin’s long-term resilience.
Weight Management & Metabolic Peptides
Achieving and maintaining a healthy weight isn’t always as straightforward as eating a balanced diet and exercising regularly. Your genetics, stress levels, age, insulin sensitivity, and a variety of other factors—controllable and not—affect your cravings, metabolism, and body composition. For example, your metabolism naturally declines with age, but can also fluctuate in response to hormonal shifts.
These underlying biological changes can limit the progress you make with healthy habits, which can be disheartening and, despite your best efforts, increase your health risks. At Pearlman Aesthetic Surgery, we take a comprehensive approach to metabolic wellness with peptide injections in Manhattan, using peptides such as:
- GLP-1 Agonists: Regulate appetite on a cellular level and stabilize blood sugar levels.
- Tesamorelin: Targets visceral fat and improves metabolic function.
GLP-1 agonists, such as semaglutide and tirzepatide, mimic the natural GLP-1 (glucagon-like peptide-1) hormones your body produces. These hormones regulate food cravings, slow digestion, and improve insulin function—quieting “food noise” to simplify dieting while also preventing dramatic spikes in your blood sugar.
Tesamorelin stimulates the pituitary gland, causing it to release growth factors. These growth factors work to reduce visceral fat, significantly lowering your health risks while supporting lean muscle mass development.
At Pearlman Aesthetic Surgery, we use these science-backed peptides to support sustainable weight loss. While these therapies restore natural metabolic balance, they’re most effective when you practice healthy habits. Our providers closely monitor your progress, providing ongoing nutritional and exercise guidance so this becomes more than a treatment—making this a turning point for your long-term health and confidence.
Additional Treatments for Weight Loss
We can’t emphasize enough that peptides are most effective when they’re part of a holistic, multi-faceted approach to body composition. That’s why Pearlman Aesthetic Surgery created The YNGR Program, which pairs GLP-1 peptides with hormone replacement therapy, wellness infusions (IVs), and ongoing support and epigenetic testing.
This personalized program combines scientifically grounded therapies to account for the wide range of underlying factors that affect your metabolism and body composition, so you can reclaim control over your health.
→ Learn More About Hormone Replacement Therapy in Manhattan
Once you’ve achieved your goal weight, we offer surgical and non-surgical body contouring procedures to complete your transformation. For example, a patient who’s lost significant weight in their abdomen may be left with loose skin, which they feel overshadows their progress. Procedures like a tummy tuck remove that excess skin, allowing your refined silhouette to shine.

For individuals struggling with mild skin laxity after weight loss, surgery isn’t the only option. We also offer Sofwave to tighten skin on the face and body with no downtime. However, because these treatments work by repairing your skin rather than removing it, they’re not suitable for patients with significant collagen loss.
Our professionals will evaluate your skin quality during your consultation to determine which approach is best for you, ensuring you love how you look and feel after completing your peptide protocol.
Hair Growth Peptides
About 70% of men and 50% of women experience hair loss at some point in their lives. While hair loss becomes increasingly more common with age, hormonal shifts and stress can also trigger excessive shedding and slowed growth.
At Pearlman Aesthetic Surgery, we offer peptide injections in Manhattan that support every stage of the hair growth cycle, including:
- GHK-Cu (Copper): Enhances circulation to improve follicles’ thickness and health.
- PTD-DBM: Encourages new growth and may reverse follicle miniaturization.
- TB-500 (Thymosin Beta-4): Reduces inflammation and helps heal damaged follicles.
Peptides play an important role in many processes that maintain your hair’s health. For example, they tell your body when to produce collagen, which keeps your hair strong and prevents split ends. Peptides also improve blood flow to the scalp and help hair follicles receive more nutrients and oxygen, promoting healthier growth.
Additional Treatments for Hair Restoration
Hair loss is a complex condition that requires intentional treatment. Often, multiple factors are responsible. That’s why at Pearlman Aesthetic Surgery, hair restoration goes beyond a single treatment.

For example, we may recommend combining targeted peptide injections with platelet-rich fibrin (PRF) or platelet-derived growth factors (PDGF). Derived from a sample of your blood, these regenerative biologics work synergistically with peptides to nourish the scalp, enhance circulation, and reactivate dormant follicles.
We also account for your hormones’ role in your hair’s health, as everything from your sex hormones to your cortisol or “stress” hormones can trigger hair loss. Our specialists will assess your hormone profile to determine if an imbalance could be responsible for your hair concerns, and integrate hormone replacement therapy into your plan.
It’s Time to Invest in Yourself
In the city that never sleeps, chronic stress is more than an inconvenience; it’s a biological disruptor that breaks down collagen, accelerates aging, disrupts your hormones, and drains your energy. Designed to address the toll that stress takes on your body, our peptide injections in Manhattan allow New Yorkers to thrive in every way, at every age.
Led by award-winning plastic surgeon Dr. Steven Pearlman, we don’t settle for anything less—because true wellness goes beyond treating symptoms.
Schedule your consultation at Pearlman Aesthetic Surgery to unlock your potential.